Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 2/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038734 | 0.90 | PLG (0.47) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7043617 | 0.89 | PLG (0.47) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7020069 | 0.86 | PLG (0.49) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL1740223 | 0.85 | PLG (0.49) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8529439 | 0.85 | PLG (0.49) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8526347 | 0.82 | PLG (0.40) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8526348 | 0.81 | PLG (0.40) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7170375 | 0.81 | PLG (0.43) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7165117 | 0.81 | PLAU (0.43) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL7170050 | 0.81 | PLG (0.43) | PLGPLAUF10KLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |