Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PNP | P00491 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533690 | 0.89 | KDM4E (0.52) | LMNAL3MBTL1TDP1KDM4EPNP | |
| SCHEMBL6484167 | 0.89 | LMNA (0.40) | LMNAL3MBTL1TDP1KDM4EPNP | |
| SCHEMBL8839893 | 0.83 | LMNA (0.36) | LMNAL3MBTL1TDP1KDM4EPNP | |
| SCHEMBL5551085 | 0.81 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPNP | |
| SCHEMBL29344590 | 0.81 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPNP | |
| SCHEMBL724112 | 0.81 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPNP | |
| SCHEMBL8533676 | 0.81 | KDM4E (0.56) | LMNAL3MBTL1TDP1KDM4EPNP | |
| SCHEMBL9444652 | 0.81 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPNP | |
| SCHEMBL17833157 | 0.79 | ANPEP (0.41) | LMNAL3MBTL1TDP1KDM4E | |
| E968 SCHEMBL17062 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675105-B1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET SA (FR) | 1998-12-23 | — | — | EP | disclosed |
| US-5693311-A | Polyiodinated compounds, process for preparing them and diagnostic compositions | GUERBET S.A. (FR) | 1997-12-02 | — | — | US | disclosed |
| US-5618977-A | Polyiodinated compounds, process of preparation and contrast agent containing them | GUERBET S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0675105-A1 | Polyiodinated compounds, process for their preparation and diagnostic composition | GUERBET S.A. (FR) | 1995-10-04 | — | — | EP | disclosed |
| EP-0656884-A1 | NOVEL POLY-IODATED COMPOUNDS, METHOD OF PREPARATION AND CONTRAST PRODUCT CONTAINING SAME | GUERBET S.A. (FR) | 1995-06-14 | — | — | EP | disclosed |