SCHEMBL8529958

SCHEMBL8529958

Cc1ccc(Nc2ccc(NC(C)C)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 4/20 0.53
P2RY4 P51582 4/20 0.53
PTPN1 P18031 1/20 0.52
CDC25A P30304 1/20 0.52
CDC25B P30305 1/20 0.52
MAPT P10636 5/20 0.50
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
HTT P42858 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MITF O75030 1/20 0.50
LMNA P02545 5/20 0.49
MAPK1 P28482 5/20 0.49
L3MBTL1 Q9Y468 4/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
POLB P06746 2/20 0.49
HPGD P15428 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31261219 1.00 P2RY2 (0.53) P2RY2P2RY4PTPN1CDC25ACDC25B
SCHEMBL29352213 0.91 P2RY2 (0.60) P2RY2P2RY4PTPN1CDC25ACDC25B
SCHEMBL35556 0.91 P2RY2 (0.60) P2RY2P2RY4PTPN1CDC25ACDC25B
SCHEMBL14092342 0.89 CDC25A (0.49) P2RY2P2RY4CDC25ACDC25BMAPT
SCHEMBL10808856 0.88 GNG2 (0.53) P2RY2P2RY4MAPTNPC1RAB9A
SCHEMBL21817605 0.88 P2RY2 (0.58) P2RY2P2RY4PTPN1CDC25ACDC25B
SCHEMBL11798485 0.87 MAPK1 (0.48) P2RY2P2RY4PTPN1CDC25ACDC25B
SCHEMBL10809992 0.87 GNG2 (0.54) P2RY2P2RY4MAPTNPC1RAB9A
SCHEMBL92477 0.85 P2RY2 (0.55) P2RY2P2RY4PTPN1CDC25ACDC25B
SCHEMBL30513727 0.85 P2RY2 (0.55) P2RY2P2RY4PTPN1CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5783518-A Dye diffusion thermal transfer printing ZENECA LIMITED (GB) 1998-07-21 US claimed
US-4824437-A ANTHRAQUINONE DYE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-04-25 US claimed
CN-106517865-A Coupling agent special for flexible macromolecular polymer bonding mortar and preparation method thereof 徐州工程学院 2017-03-22 CN disclosed
US-20080187666-A1 PROCESS FOR PRINTING TEXTILE FIBRE MATERIALS IN ACCORDANCE WITH THE INK-JET PRINTING PROCESS HUNTSMAN INTERNATIONAL LLC (US) 2008-08-07 US disclosed
US-20080187666-A1 PROCESS FOR PRINTING TEXTILE FIBRE MATERIALS IN ACCORDANCE WITH THE INK-JET PRINTING PROCESS HUNTSMAN INTERNATIONAL LLC (US) 2008-08-07 US disclosed
US-20070226919-A1 Method for Dyeing or Printing Textile Materials HUNTSMAN INTERNATIONAL LLC (US) 2007-10-04 US disclosed
US-20070226919-A1 Method for Dyeing or Printing Textile Materials HUNTSMAN INTERNATIONAL LLC (US) 2007-10-04 US disclosed
US-20070058014-A1 Process for printing textile fibre materials in accordance with the ink-jet printing process HUNTSMAN INTERNATIONAL LLC 2007-03-15 US disclosed
US-20070058014-A1 Process for printing textile fibre materials in accordance with the ink-jet printing process HUNTSMAN INTERNATIONAL LLC 2007-03-15 US disclosed