Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | PARP1 | P09874 | 4/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | TYMS | P04818 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20327023 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL20327033 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL9252606 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL9298476 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL8485108 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL8488865 | 0.84 | KDM4E (0.57) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL9216843 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL20511734 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL12388167 | 0.83 | TRPV1 (0.58) | KDM4EALDH1A1GAAMAPTNPC1 | |
| SCHEMBL9817824 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1GAAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028134-A1 | PROCESS FOR PREPARING QUINAZOLONES | HOECHST CELANESE CORPORATION (US) | 1997-08-07 | — | — | WO | claimed |
| US-8815879-B2 | Substituted 4-(selenophen-2(or-3)-ylamino)pyrimidine compounds and methods of use thereof | KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITED (US) | 2014-08-26 | — | — | US | disclosed |
| US-20130266563-A1 | SUBSTITUTED 4-(SELENOPHEN-2(OR-3)-YLAMINO)PYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITED (IN) | 2013-10-10 | — | — | US | disclosed |
| US-5763608-A | DEHYDRATION A N-ACYL BETA AMINO ACID TO FORM AN OXAZONE, ADDING A CARBOXYLIC ACID, DISTILLATION AND HEATING | HOECHST CELANESE CORPORATION (US) | 1998-06-09 | — | — | US | disclosed |
| US-5739330-A | DEHYDRATING AN N-ACYL BETA AMINO ACID TO FORM OXAZONE, ADDING CARBOXYLIC ACID AND AMINE SALT, DISTILLING TO FORM QUINAZOLONE | HOECHST CELANESE CORPORATION (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997028118-A1 | PROCESS FOR PREPARING ANTHRANILIC ACIDS | HOECHST CELANESE CORPORATION (US) | 1997-08-07 | — | — | WO | disclosed |
| WO-1997028134-A1 | PROCESS FOR PREPARING QUINAZOLONES | HOECHST CELANESE CORPORATION (US) | 1997-08-07 | — | — | WO | disclosed |
| WO-1997028132-A1 | PROCESS FOR PREPARING PYRIMIDIN DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1997-08-07 | — | — | WO | disclosed |
| US-5395838-A | Aromatic aminomethyl substitutes compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | disclosed |
| EP-0373891-B1 | Anti-tumour agents | ICI PLC (GB) | 1994-11-02 | — | — | EP | disclosed |
| WO-1994007869-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |
| US-5280027-A | Quinazoline containing compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |
| EP-0284338-B1 | Anti-tumour agents | ICI PLC (GB) | 1993-12-22 | — | — | EP | disclosed |
| US-5252573-A | Quinazoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-12 | — | — | US | disclosed |
| US-5089499-A | Anticarcinogenic agents; thymidylate synthetase inhibitors; antiallergens; psoriasis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |
| EP-0459730-A2 | Anti-tumour compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |
| US-4981856-A | QUINAZOLINE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-01 | — | — | US | disclosed |
| EP-0373891-A2 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |
| EP-0284338-A2 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130266563-A1 | SUBSTITUTED 4-(SELENOPHEN-2(OR-3)-YLAMINO)PYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | RPS6, SULT1E1, SCLY | KDM4E 2187/4885ALDH1A1 2281/4885GAA 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.