Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 3/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840626 | 0.81 | GRM8 (0.44) | GRM8GRM6GRM2GRM3SLC1A2 | |
| Hydrochloric Acid SCHEMBL5840618 | 0.80 | TDP1 (0.43) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL8358694 | 0.80 | SLC1A2 (0.40) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL5840782 | 0.79 | GRM2 (0.45) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL5840517 | 0.79 | GRM2 (0.49) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL15144264 | 0.79 | FABP7 (0.44) | FABP7FABP5DDB1CRBNTSHR | |
| SCHEMBL5841867 | 0.77 | GRM2 (0.50) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL6466259 | 0.77 | GRM2 (0.50) | GRM8GRM6GRM2GRM3SLC1A2 | |
| Hydrochloric Acid SCHEMBL5841578 | 0.76 | GRM2 (0.47) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL5840776 | 0.76 | SLC1A2 (0.48) | GRM8GRM6GRM2GRM3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696577-B1 | Synthetic excitatory amino acids | LILLY CO ELI (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996005175-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 1996-02-22 | — | — | WO | disclosed |
| EP-0696577-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |