Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22334802 | 0.81 | CHRM2 (0.33) | CHRM2CHRM5CHRM1 | |
| SCHEMBL13561266 | 0.81 | CHRM2 (0.33) | CHRM2CHRM5CHRM1 | |
| SCHEMBL29957418 | 0.72 | CHRM2 (0.36) | CHRM2CHRM5CHRM1 | |
| SCHEMBL23261024 | 0.69 | CHRM2 (0.34) | CHRM2CHRM5CHRM1 | |
| SCHEMBL23261025 | 0.69 | CHRM2 (0.34) | CHRM2CHRM5CHRM1 | |
| SCHEMBL2757715 | 0.68 | KMT2A (0.35) | CHRM2CHRM5CHRM1 | |
| SCHEMBL23321573 | 0.68 | KMT2A (0.35) | CHRM2CHRM5CHRM1 | |
| SCHEMBL6706088 | 0.68 | KMT2A (0.35) | CHRM2CHRM5CHRM1 | |
| SCHEMBL14009825 | 0.68 | CHRM2 (0.33) | CHRM2CHRM5CHRM1 | |
| SCHEMBL6361339 | 0.68 | KMT2A (0.35) | CHRM2CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873347-A2 | NOVEL AMINE DERIVATIVES OF EPIPODOPHYLLOTOXIN 2\", 3\"-DIDEOXYGLYCOSIDES, PREPARATION METHOD THEREFOR AND USE THEREOF AS A DRUG AND FOR TREATING CANCER | PIERRE FABRE MEDICAMENT (FR) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997013776-A2 | NOVEL AMINE DERIVATIVES OF EPIPODOPHYLLOTOXIN 2', 3'-DIDEOXYGLYCOSIDES, PREPARATION METHOD THEREFOR AND USE THEREOF AS A DRUG AND FOR TREATING CANCER | PIERRE FABRE MEDICAMENT (FR) | 1997-04-17 | — | — | WO | disclosed |