Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13561266 | 1.00 | CHRM2 (0.33) | CHRM2CHRM5CHRM1THRBLMNA | |
| SCHEMBL8530228 | 0.81 | CHRM2 (0.31) | CHRM2CHRM5CHRM1 | |
| SCHEMBL25141269 | 0.79 | CHRM5 (0.33) | CHRM2CHRM5CHRM1 | |
| SCHEMBL9604672 | 0.78 | THRB (0.44) | CHRM2CHRM5CHRM1THRBLMNA | |
| SCHEMBL25141242 | 0.78 | TDP1 (0.33) | CHRM2CHRM5CHRM1 | |
| SCHEMBL25141289 | 0.76 | ALDH1A1 (0.35) | CHRM2CHRM5CHRM1 | |
| SCHEMBL29957418 | 0.75 | CHRM2 (0.36) | CHRM2CHRM5CHRM1LMNA | |
| SCHEMBL25141266 | 0.74 | CHRM2 (0.30) | CHRM2CHRM5CHRM1 | |
| SCHEMBL21095311 | 0.74 | — | — | |
| SCHEMBL22837183 | 0.72 | THRB (0.42) | CHRM2CHRM5CHRM1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3693361-A1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTA-HYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL) CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE | Parion Sciences, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |