Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.78 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.78 |
| ▸ | AR | P10275 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.78 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.76 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.76 |
| ▸ | DRD3 | P35462 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370141 | 1.00 | PGR (0.78) | PGRCYP3A4ABCB11CYP2C19ADORA3 | |
| SCHEMBL9523036 | 1.00 | PGR (0.78) | PGRCYP3A4ABCB11CYP2C19ADORA3 | |
| SCHEMBL11698048 | 0.91 | PGR (0.68) | PGRCYP3A4ABCB11CYP2C19ADORA3 | |
| SCHEMBL11698044 | 0.91 | PGR (0.68) | PGRCYP3A4ABCB11CYP2C19ADORA3 | |
| Norethindrone Acetate SCHEMBL14577826 | 0.87 | CYP3A4 (1.00) | PGRCYP3A4ABCB11CYP2C19ADORA3 | |
| Norethindrone Acetate SCHEMBL14360522 | 0.87 | CYP3A4 (1.00) | PGRCYP3A4ABCB11CYP2C19ADORA3 | |
| Norethindrone Acetate SCHEMBL11321479 | 0.87 | CYP3A4 (1.00) | PGRCYP3A4ABCB11CYP2C19ADORA3 | |
| Norethindrone Acetate SCHEMBL1232662 | 0.87 | CYP3A4 (1.00) | PGRCYP3A4ABCB11CYP2C19ADORA3 | |
| Norethindrone Acetate SCHEMBL37530 | 0.87 | CYP3A4 (1.00) | PGRCYP3A4ABCB11CYP2C19ADORA3 | |
| Norethindrone Acetate SCHEMBL14074495 | 0.87 | CYP3A4 (1.00) | PGRCYP3A4ABCB11CYP2C19ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770227-A | Progesterone replacement therapy | ALZA CORPORATION (US) | 1998-06-23 | — | — | US | claimed |
| US-5633011-A | Progesterone replacement therapy | ALZA CORPORATION (US) | 1997-05-27 | — | — | US | claimed |
| EP-0500793-B1 | OSMOTIC, ORAL DOSAGE FORM FOR FERTILITY CONTROL | ALZA CORP (US) | 1993-11-03 | — | — | EP | claimed |
| EP-0472645-B1 | OSMOTIC DOSAGE FORM | ALZA CORPORATION (US) | 1993-07-14 | — | — | EP | claimed |
| US-5200197-A | Contraceptive pill | ALZA CORPORATION (US) | 1993-04-06 | — | — | US | claimed |
| EP-0500793-A1 | OSMOTIC, ORAL DOSAGE FORM FOR FERTILITY CONTROL. | ALZA CORP (US) | 1992-09-02 | — | — | EP | claimed |
| US-5098714-A | OSMOTIC, ORAL DOSAGE FORM FOR FERTILITY CONTROL | ALZA CORPORATION (US) | 1992-03-24 | — | — | US | claimed |
| WO-1991007173-A1 | OSMOTIC, ORAL DOSAGE FORM FOR FERTILITY CONTROL | ALZA CORPORATION (US) | 1991-05-30 | — | — | WO | claimed |
| US-4948593-A | SUSTAINED AND CONTROLLED CONTRACEPTION | ALZA CORPORATION (US) | 1990-08-14 | — | — | US | claimed |
| US-4066757-A | Oral contraceptive regimen | ORTHO PHARMACEUTICAL CORPORATION (US) | 1978-01-03 | — | — | US | claimed |
| US-5842476-A | Method for controlling fertility | ALZA CORPORATION (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0500793-B1 | OSMOTIC, ORAL DOSAGE FORM FOR FERTILITY CONTROL | ALZA CORP (US) | 1993-11-03 | — | — | EP | disclosed |
| EP-0472645-B1 | OSMOTIC DOSAGE FORM | ALZA CORPORATION (US) | 1993-07-14 | — | — | EP | disclosed |
| US-5200197-A | Contraceptive pill | ALZA CORPORATION (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0500793-A1 | OSMOTIC, ORAL DOSAGE FORM FOR FERTILITY CONTROL. | ALZA CORP (US) | 1992-09-02 | — | — | EP | disclosed |
| EP-0472645-A1 | OSMOTIC DOSAGE FORM. | ALZA CORP (US) | 1992-03-04 | — | — | EP | disclosed |
| WO-1991007173-A1 | OSMOTIC, ORAL DOSAGE FORM FOR FERTILITY CONTROL | ALZA CORPORATION (US) | 1991-05-30 | — | — | WO | disclosed |
| WO-1990014075-A1 | OSMOTIC DOSAGE FORM | ALZA CORPORATION (US) | 1990-11-29 | — | — | WO | disclosed |
| US-4948593-A | SUSTAINED AND CONTROLLED CONTRACEPTION | ALZA CORPORATION (US) | 1990-08-14 | — | — | US | disclosed |
| US-4066757-A | Oral contraceptive regimen | ORTHO PHARMACEUTICAL CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |