Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.74 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.74 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157968 | 1.00 | ITGB3 (0.74) | ITGB3ITGA2BSLC7A5PTPN1ACACB | |
| SCHEMBL157969 | 1.00 | ITGB3 (0.74) | ITGB3ITGA2BSLC7A5PTPN1ACACB | |
| Hydrochloric Acid SCHEMBL16816256 | 0.98 | ITGB3 (0.72) | ITGB3ITGA2BSLC7A5PTPN1ACACB | |
| Hydrochloric Acid SCHEMBL16816253 | 0.98 | ITGB3 (0.72) | ITGB3ITGA2BSLC7A5PTPN1ACACB | |
| SCHEMBL4551608 | 0.97 | ITGB3 (0.74) | ITGB3ITGA2BLMNA | |
| SCHEMBL4551607 | 0.97 | ITGB3 (0.74) | ITGB3ITGA2BLMNA | |
| SCHEMBL1960615 | 0.96 | ITGB3 (0.77) | ITGB3ITGA2BPTPN1LMNA | |
| SCHEMBL1960616 | 0.96 | ITGB3 (0.77) | ITGB3ITGA2BPTPN1LMNA | |
| SCHEMBL7142926 | 0.96 | ITGB3 (0.77) | ITGB3ITGA2BPTPN1LMNA | |
| SCHEMBL31193421 | 0.96 | ITGB3 (0.77) | ITGB3ITGA2BPTPN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873357-A2 | ANTITHROMBOTIC AGENTS AND METHODS OF USE | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5672585-A | HYDROPHOBIC AND CATIONIC AMINO ACID-CONTAINING CYCLIC (POLY)PEPTIDES HAVING HIGH AFFINITY FOR GLYCOPROTEIN IIB/IIIA RECEPTORS TO INHIBIT PLATELET AGGREGATION WITHOUT PROLONGED BLEEDING | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1997-09-30 | — | — | US | disclosed |
| WO-1997025343-A2 | ANTITHROMBOTIC AGENTS AND METHODS OF USE | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1997-07-17 | — | — | WO | disclosed |
| WO-1995000544-A1 | METHOD AND COMPOSITION FOR TREATING THROMBOSIS | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1995-01-05 | — | — | WO | disclosed |