Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 7/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530279 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL8530283 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL15678905 | 0.86 | DPP4 (0.40) | — | |
| SCHEMBL8529074 | 0.86 | KDM1A (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4KDM1A | |
| SCHEMBL8529070 | 0.86 | KDM1A (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4KDM1A | |
| SCHEMBL8529080 | 0.86 | KDM1A (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4KDM1A | |
| SCHEMBL8531166 | 0.82 | ABCC9 (0.35) | KDM1AKCNH2KDM1BTACR1 | |
| SCHEMBL8531160 | 0.82 | ABCC9 (0.35) | KDM1AKCNH2KDM1BTACR1 | |
| SCHEMBL8531161 | 0.82 | ABCC9 (0.35) | KDM1AKCNH2KDM1BTACR1 | |
| SCHEMBL6669105 | 0.78 | MAPT (0.40) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |
| EP-0720609-B1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LTD (GB) | 1998-11-11 | — | — | EP | disclosed |
| US-5703240-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |