SCHEMBL8530284

SCHEMBL8530284

COc1ccc(-c2[c]ccc([N+](=O)[O-])c2)c(OC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HTT P42858 3/20 0.43
TLR9 Q9NR96 1/20 0.43
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 4/20 0.41
MAPT P10636 3/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
SNCA P37840 2/20 0.41
CTSV O60911 1/20 0.41
CTSL P07711 1/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2E1 P05181 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10887956 0.83 HTT (0.45) KMT2AMEN1L3MBTL1HTTTDP1
SCHEMBL6189588 0.81 CYP1A1 (0.51) KMT2AMEN1L3MBTL1HTTKDM4E
SCHEMBL9476182 0.80 APP (0.50) KMT2AMEN1L3MBTL1HTTKDM4E
SCHEMBL8531162 0.78 ALDH1A1 (0.45) KMT2AMEN1HTTTDP1ALDH1A1
SCHEMBL10169410 0.76 APP (0.55) KMT2AMEN1L3MBTL1HTTTLR9
SCHEMBL8532282 0.76 CYP1A1 (0.46) KMT2AMEN1L3MBTL1HTTKDM4E
SCHEMBL28016905 0.75 KMT2A (0.51) KMT2AMEN1L3MBTL1HTTTLR9
SCHEMBL8528175 0.75 CYP1A1 (0.46) HTTALDH1A1LMNASNCACYP1A1
SCHEMBL4599680 0.73 MAPT (0.52) KMT2AMEN1L3MBTL1HTTKDM4E
SCHEMBL5324006 0.72 CYP1A1 (0.53) KMT2AMEN1L3MBTL1HTTTLR9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5749925-A Dyeing or printing process with new and known cationic 4,5-dihydro-iH-1,2,3-triazolium compounds as dyestuffs and new cationic 4,5-dihydro-1H-1,2,3-triazolium compounds BAYER AKTIENGESELLSCHAFT (DE) 1998-05-12 US disclosed