SCHEMBL8530339

SCHEMBL8530339

C=C(C)C(=O)Oc1c(Cl)cccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.45
KMT2A Q03164 2/20 0.43
ATM Q13315 1/20 0.38
ALDH1A1 P00352 3/20 0.38
CASP1 P29466 1/20 0.36
CAMK2A Q9UQM7 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NOTUM Q6P988 3/20 0.35
TSHR P16473 1/20 0.34
AKR1B1 P15121 1/20 0.34
PTPN7 P35236 1/20 0.34
PTPN12 Q05209 1/20 0.34
PTPN22 Q9Y2R2 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528074 0.90 KDM4E (0.42) ELANEKMT2AATMALDH1A1CASP1
SCHEMBL28412935 0.84 SMN1; SMN2 (0.42) KMT2AALDH1A1KDM4EHSD17B10TSHR
Acrylic Acid Ethyl Ester SCHEMBL8861606 0.83 MAPT (0.42) ELANEKMT2AALDH1A1CASP1KDM4E
SCHEMBL1573908 0.82 ELANE (0.39) ELANEKMT2AATMALDH1A1KDM4E
SCHEMBL9066800 0.81 ELANE (0.42) ELANEKMT2AATMALDH1A1KDM4E
SCHEMBL964110 0.81 ELANE (0.49) ELANEKMT2AATMALDH1A1CASP1
SCHEMBL3838756 0.80 ELANE (0.47) ELANEKMT2AATMALDH1A1KDM4E
SCHEMBL3006462 0.79 KDM4E (0.48) KMT2AALDH1A1KDM4EHSD17B10TSHR
SCHEMBL15759425 0.79 KMT2A (0.39) KMT2AALDH1A1CAMK2AKDM4EHSD17B10
SCHEMBL10407840 0.78 ELANE (0.46) ELANEKMT2AATMALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584359-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI PHOTO FILM CO LTD (JP) 1998-10-28 EP disclosed
EP-0581956-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI PHOTO FILM CO LTD (JP) 1998-08-12 EP disclosed
EP-0535251-B1 ELECTROPHOTOGRAPHIC LITHOGRAPHIC PRINTING PLATE FUJI PHOTO FILM CO LTD (JP) 1997-07-30 EP disclosed
US-5624777-A Electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1997-04-29 US disclosed
EP-0363928-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1997-01-02 EP disclosed
EP-0535236-B1 NEGATIVE PLATE FOR ELECTROPHOTOGRAPHIC LITHOGRAPHIC PRINTING FUJI PHOTO FILM CO LTD (JP) 1996-12-18 EP disclosed
EP-0361063-B1 Electrophotograhic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1996-12-11 EP disclosed
US-5580690-A LOW-MOLECULAR-WEIGHT ACRYLATE BINDER RESIN BASED ON A MACROMONOMER AND A MONOMER HAVING A POLAR GROUP; SCANNING EXPOSURE SYSTEM USING A SEMICONDUCTOR LASER BEAM; HEAT AND MOISTURE RESISTANCE; OFFSET PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1996-12-03 US disclosed
EP-0352697-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1996-11-20 EP disclosed
US-5573879-A ACRYLIC POLYMERS FUJI PHOTO FILM CO., LTD. (JP) 1996-11-12 US disclosed
EP-0416591-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-03-13 EP disclosed
EP-0410324-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD (JP) 1991-01-30 EP disclosed
EP-0405499-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-02 EP disclosed
EP-0399469-A1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-11-28 EP disclosed
EP-0398373-A1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-11-22 EP disclosed
EP-0389928-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-10-03 EP disclosed
US-4954407-A Modified methacrylate polymer FUJI PHOTO FILM CO., LTD. (JP) 1990-09-04 US disclosed
EP-0362804-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP disclosed
EP-0361063-A2 Electrophotograhic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-04-04 EP disclosed
EP-0357039-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP disclosed