SCHEMBL8528074

SCHEMBL8528074

C=C(C)C(=O)Oc1c(C)cccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ELANE P08246 1/20 0.41
KMT2A Q03164 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PTPN1 P18031 1/20 0.38
POLB P06746 1/20 0.38
CASP1 P29466 1/20 0.36
ATM Q13315 2/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
HDAC4 P56524 1/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530339 0.90 ELANE (0.45) KDM4EALDH1A1HSD17B10ELANEKMT2A
SCHEMBL447625 0.88 ALDH1A1 (0.49) KDM4EALDH1A1HPGDHSD17B10ELANE
SCHEMBL9501805 0.82 KDM4E (0.61) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL15496003 0.81 KDM4E (0.44) KDM4EALDH1A1HPGDHSD17B10ELANE
SCHEMBL8415463 0.79 KDM4E (0.71) KDM4EALDH1A1HPGDHSD17B10ELANE
SCHEMBL28412935 0.78 SMN1; SMN2 (0.42) KDM4EALDH1A1HPGDHSD17B10KMT2A
Acrylic Acid Ethyl Ester SCHEMBL8861606 0.77 MAPT (0.42) KDM4EALDH1A1HPGDHSD17B10ELANE
SCHEMBL10499684 0.77 KDM4E (0.39) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL10050181 0.76 ATM (0.43) KDM4EALDH1A1HPGDHSD17B10ELANE
SCHEMBL1623445 0.76 KDM4E (0.50) KDM4EALDH1A1HPGDHSD17B10ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584359-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI PHOTO FILM CO LTD (JP) 1998-10-28 EP disclosed
EP-0581956-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI PHOTO FILM CO LTD (JP) 1998-08-12 EP disclosed
US-5624777-A Electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1997-04-29 US disclosed
EP-0363928-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1997-01-02 EP disclosed
EP-0361063-B1 Electrophotograhic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1996-12-11 EP disclosed
US-5580690-A LOW-MOLECULAR-WEIGHT ACRYLATE BINDER RESIN BASED ON A MACROMONOMER AND A MONOMER HAVING A POLAR GROUP; SCANNING EXPOSURE SYSTEM USING A SEMICONDUCTOR LASER BEAM; HEAT AND MOISTURE RESISTANCE; OFFSET PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1996-12-03 US disclosed
EP-0352697-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1996-11-20 EP disclosed
US-5573879-A ACRYLIC POLYMERS FUJI PHOTO FILM CO., LTD. (JP) 1996-11-12 US disclosed
US-5558966-A RESIN WITH POLAR GROUPS, BLOCK POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1996-09-24 US disclosed
EP-0439072-B1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1996-04-03 EP disclosed
EP-0432727-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-06-19 EP disclosed
US-5009975-A Binder resin blend, moisture resistant FUJI PHOTO FILM CO., LTD. (JP) 1991-04-23 US disclosed
EP-0399469-A1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-11-28 EP disclosed
EP-0398373-A1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-11-22 EP disclosed
EP-0389928-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-10-03 EP disclosed
US-4954407-A Modified methacrylate polymer FUJI PHOTO FILM CO., LTD. (JP) 1990-09-04 US disclosed
EP-0363928-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-04-18 EP disclosed
EP-0361063-A2 Electrophotograhic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-04-04 EP disclosed
EP-0361514-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-04-04 EP disclosed
EP-0357039-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP disclosed