Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13629596 | 0.85 | TACR1 (0.46) | TACR1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL8176205 | 0.84 | TACR1 (0.48) | TACR1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL13630147 | 0.82 | TACR1 (0.46) | TACR1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL310305 | 0.81 | TACR1 (0.44) | TACR1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL8530490 | 0.80 | NOTUM (0.46) | TACR1MAPTALDH1A1HPGD | |
| SCHEMBL5198211 | 0.80 | TACR1 (0.43) | TACR1 | |
| SCHEMBL4135034 | 0.80 | TACR1 (0.48) | TACR1 | |
| SCHEMBL5199411 | 0.80 | TACR1 (0.48) | TACR1 | |
| SCHEMBL3157091 | 0.79 | TACR1 (0.58) | TACR1 | |
| SCHEMBL6424614 | 0.79 | TACR1 (0.47) | TACR1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |
| US-5703240-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |