Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28154335 | 1.00 | CA2 (0.35) | CA2MEN1POLBKMT2ACYP3A4 | |
| SCHEMBL28168369 | 0.88 | MEN1 (0.50) | CA2MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL18323717 | 0.87 | MEN1 (0.50) | CA2MEN1POLBKMT2ACYP3A4 | |
| SCHEMBL19554733 | 0.87 | MEN1 (0.45) | CA2MEN1POLBKMT2ACYP3A4 | |
| SCHEMBL4545007 | 0.87 | MEN1 (0.50) | CA2MEN1POLBKMT2ACYP3A4 | |
| SCHEMBL22953317 | 0.87 | MEN1 (0.50) | CA2MEN1POLBKMT2ACYP3A4 | |
| SCHEMBL9191084 | 0.87 | MEN1 (0.45) | CA2MEN1POLBKMT2ACYP3A4 | |
| SCHEMBL3281247 | 0.85 | MEN1 (0.30) | MEN1POLBKMT2A | |
| SCHEMBL24874181 | 0.83 | BCHE (0.39) | MEN1POLBKMT2ACYP3A4TSHR | |
| SCHEMBL10835191 | 0.80 | CA2 (0.44) | CA2MEN1KMT2ACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760198-A | Process for preparation of 4\"-deoxyerythromycins A and B | ABBOTT LABORATORIES (US) | 1998-06-02 | — | — | US | disclosed |