Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2442181 | 0.86 | PHF8 (0.48) | SMN1; SMN2LMNA | |
| SCHEMBL2548314 | 0.81 | CYP1A2 (0.47) | SLC22A6TSHREPHX2SMN1; SMN2LMNA | |
| SCHEMBL7746718 | 0.80 | FAAH (0.54) | MEN1MAPTKMT2A | |
| SCHEMBL7742822 | 0.78 | FAAH (0.63) | EPHX2MEN1KMT2A | |
| SCHEMBL10557329 | 0.78 | TSHR (0.41) | TSHRSMN1; SMN2LMNANFKB1MAPT | |
| SCHEMBL7784202 | 0.77 | FAAH (0.61) | SLC22A6TSHREPHX2HSD17B10AKR1B1 | |
| SCHEMBL14661992 | 0.77 | FAAH (0.67) | EPHX2MEN1KMT2A | |
| SCHEMBL9126413 | 0.77 | FAAH (0.67) | EPHX2MEN1KMT2A | |
| SCHEMBL11332591 | 0.77 | FAAH (0.67) | EPHX2MEN1KMT2A | |
| SCHEMBL9637545 | 0.77 | FAAH (0.67) | EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783703-A | CARBAPENEM INTERMEDIATES | LEDERLE (JAPAN), LTD. (JP) | 1998-07-21 | — | — | US | disclosed |
| US-5679790-A | ANTIBIOTICS, BACTERICIDES | LEDERLE (JAPAN), LTD. (JP) | 1997-10-21 | — | — | US | disclosed |