SCHEMBL8530923

SCHEMBL8530923

O=C(O)C(=O)NCCC(F)=C(F)F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM5B Q9UGL1 1/20 0.32
ECE1 P42892 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530840 0.88 PLA2G2A (0.31) PLA2G2ALMNASMN1; SMN2
SCHEMBL8527901 0.80 GAA (0.36)
SCHEMBL27536224 0.78 KDM4E (0.38) LMNA
SCHEMBL27564321 0.77 TET2 (0.45) PLA2G2A
SCHEMBL12999522 0.75 ECE1 (0.50) PLA2G2ALMNAKDM5BECE1
SCHEMBL8533062 0.74 TDP1 (0.33)
SCHEMBL9112416 0.74 KDM4E (0.48) SMN1; SMN2
SCHEMBL2175844 0.74 KDM5B (0.47) PLA2G2ALMNAKDM5B
Hydrochloric Acid SCHEMBL13726042 0.73 PLA2G2A (0.48) PLA2G2ALMNAKDM5BECE1
SCHEMBL9114630 0.71 MEN1 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640069-B1 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO CO (US) 1998-11-04 EP disclosed
US-5714517-A NEMATOCIDES, INSECTICIDES MONSANTO COMPANY (US) 1998-02-03 US disclosed
US-5693865-A Fluoroalkenyl compounds and their use as pest repellents MONSANTO COMPANY (US) 1997-12-02 US disclosed
EP-0798285-A2 3,4,4-Trifluoro-3-butenoic acid or its methyl ester MONSANTO COMPANY (US) 1997-10-01 EP disclosed
US-5623084-A INSECTICIDES, MITICIDES MONSANTO COMPANY (US) 1997-04-22 US disclosed
US-5561162-A SYSTEMIC PESTICIDES; NEMATOCIDES; INSECTICIDES; MITICIDES; EFFICIENCY; CROPS MONSANTO COMPANY (US) 1996-10-01 US disclosed
US-5457134-A Controlling nematodes, insects, acarids on plants MONSANTO COMPANY (US) 1995-10-10 US disclosed
US-5389680-A Insecticides, nematocides, miticides MONSANTO COMPANY (US) 1995-02-14 US disclosed
WO-1992015555-A2 FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST REPELLENTS MONSANTO COMPANY (US) 1992-09-17 WO disclosed