Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.51 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.51 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894362 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 | |
| SCHEMBL10779010 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 | |
| SCHEMBL10891677 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 | |
| SCHEMBL10890371 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 | |
| SCHEMBL10889442 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 | |
| SCHEMBL10890368 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 | |
| SCHEMBL10887549 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 | |
| SCHEMBL10889905 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 | |
| SCHEMBL10889436 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 | |
| SCHEMBL10894366 | 0.99 | FAAH (0.57) | FAAHEPHX2MEN1KMT2APSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821331-A | INHIBIT THE PROTEOLYTIC ACTIVITY OF PROTEASES | ELI LILLY AND COMPANY (US) | 1998-10-13 | — | — | US | claimed |
| CN-1100426-A | Lysosomal enzyme-cleavable antitumor drug conjugates | BRISTOL MYERS SQUIBB CO (US) | 1995-03-22 | — | — | CN | claimed |
| EP-0632051-A1 | Anti-picornaviral agents | ELI LILLY AND COMPANY (US) | 1995-01-04 | — | — | EP | claimed |
| US-5821331-A | INHIBIT THE PROTEOLYTIC ACTIVITY OF PROTEASES | ELI LILLY AND COMPANY (US) | 1998-10-13 | — | — | US | disclosed |
| US-5514778-A | ENZYME INHIBITORS OF PROTEOLYTIC ENZYMES FOR RHINOVIRUSES | ELI LILLY AND COMPANY (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0632051-A1 | Anti-picornaviral agents | ELI LILLY AND COMPANY (US) | 1995-01-04 | — | — | EP | disclosed |