Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294965 | 0.86 | CYP1A2 (0.43) | CYP1A2CYP3A4PTGS1PTGS2TSHR | |
| SCHEMBL4530181 | 0.84 | PTGS1 (0.42) | CYP1A2CYP3A4PTGS1PTGS2TSHR | |
| SCHEMBL838416 | 0.84 | CYP1A2 (0.39) | CYP1A2CYP3A4PTGS1PTGS2TSHR | |
| SCHEMBL4434438 | 0.84 | CYP1A2 (0.39) | CYP1A2CYP3A4PTGS1PTGS2TSHR | |
| SCHEMBL112491 | 0.84 | CYP1A2 (0.39) | CYP1A2CYP3A4PTGS1PTGS2TSHR | |
| Hydrazine SCHEMBL22634091 | 0.82 | CYP1A2 (0.38) | CYP1A2CYP3A4PTGS1PTGS2TSHR | |
| SCHEMBL12214449 | 0.82 | CYP1A2 (0.38) | CYP1A2CYP3A4PTGS1PTGS2TSHR | |
| SCHEMBL18545144 | 0.82 | PLG (0.41) | CYP1A2CYP3A4PTGS1PTGS2TSHR | |
| SCHEMBL14519926 | 0.82 | CYP1A2 (0.38) | CYP1A2CYP3A4PTGS1PTGS2TSHR | |
| SCHEMBL4082092 | 0.80 | PLG (0.41) | CYP1A2CYP3A4PTGS1PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |