Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8530200 | 0.98 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3SMN1; SMN2KDM4E | |
| SCHEMBL8530523 | 0.92 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3SMN1; SMN2KDM4E | |
| SCHEMBL8530206 | 0.84 | SLC6A4 (0.70) | SLC6A4SLC6A2SLC6A3SMN1; SMN2KDM4E | |
| SCHEMBL11838305 | 0.83 | AGBL2 (0.47) | SLC6A4SLC6A2SLC6A3KDM4EATM | |
| SCHEMBL8531815 | 0.81 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3SMN1; SMN2KDM4E | |
| SCHEMBL8529745 | 0.81 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3SMN1; SMN2KDM4E | |
| SCHEMBL8531089 | 0.81 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3SMN1; SMN2KDM4E | |
| SCHEMBL8529763 | 0.81 | ATM (0.53) | SLC6A4SLC6A2SLC6A3KDM4EATM | |
| Maleic Acid SCHEMBL8529729 | 0.80 | AGBL2 (0.52) | SLC6A4SLC6A2SLC6A3AGBL2 | |
| Fumaric Acid SCHEMBL8529731 | 0.80 | AGBL2 (0.52) | SLC6A4SLC6A2SLC6A3AGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |