Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533118 | 1.00 | SOAT1 (0.70) | SOAT1SMN1; SMN2ALDH1A1MAPTSOAT2 | |
| SCHEMBL8537159 | 0.92 | SOAT1 (0.83) | SOAT1SMN1; SMN2ALDH1A1MAPTSOAT2 | |
| SCHEMBL8537160 | 0.92 | SOAT1 (0.83) | SOAT1SMN1; SMN2ALDH1A1MAPTSOAT2 | |
| SCHEMBL8532492 | 0.87 | SOAT1 (0.55) | SOAT1SMN1; SMN2ALDH1A1MAPTFAAH | |
| SCHEMBL8532494 | 0.87 | SOAT1 (0.55) | SOAT1SMN1; SMN2ALDH1A1MAPTFAAH | |
| SCHEMBL8537601 | 0.84 | SOAT1 (0.52) | SOAT1FAAHCNR1EPHX2 | |
| SCHEMBL8537603 | 0.84 | SOAT1 (0.52) | SOAT1FAAHCNR1EPHX2 | |
| SCHEMBL15750407 | 0.82 | HDAC3 (0.54) | SOAT1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8531915 | 0.82 | HDAC3 (0.54) | SOAT1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8536253 | 0.82 | ALDH1A1 (0.50) | SOAT1ALDH1A1MAPTTDP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801178-A | ACAT INHIBITOR, ARTERIOSCLEROSIS | NIPPON SHOJI KAISH LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0726247-B1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0726247-A1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA, LIMITED (JP) | 1996-08-14 | — | — | EP | disclosed |