Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 9/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31743440 | 0.97 | TRPM8 (0.42) | TRPM8GABBR2GABRR1GABBR1LPAR3 | |
| SCHEMBL28485915 | 0.92 | — | — | |
| SCHEMBL28671042 | 0.92 | — | — | |
| SCHEMBL28904369 | 0.92 | HPGD (0.44) | TRPM8GABBR2GABRR1GABBR1LPAR3 | |
| SCHEMBL7118204 | 0.92 | TRPM8 (0.42) | TRPM8GABBR2GABRR1GABBR1LPAR3 | |
| Potassium Ion SCHEMBL7118115 | 0.92 | TRPM8 (0.42) | TRPM8GABBR2GABRR1GABBR1LPAR3 | |
| SCHEMBL9583405 | 0.92 | — | — | |
| SCHEMBL20140630 | 0.92 | TRPM8 (0.42) | TRPM8GABBR2GABRR1GABBR1LPAR3 | |
| SCHEMBL20985752 | 0.92 | — | — | |
| SCHEMBL29019122 | 0.92 | TRPM8 (0.42) | TRPM8GABBR2GABRR1GABBR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728360-A | VANADYL PHOSPHITE OXIDATION CATALYST | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5532385-A | VANADIUM-PHOSPHONATE CATALYST | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-07-02 | — | — | US | disclosed |