SCHEMBL8533272

SCHEMBL8533272

Cc1ccc(-c2cc(Cl)c(C(=O)N=C(N)N)cc2S(C)(=O)=O)cc1

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 2/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8529312 0.90 SLC9A1 (0.63) SLC9A1
SCHEMBL8529332 0.88 SLC9A1 (1.00) SLC9A1
SCHEMBL8444840 0.87 SLC9A1 (0.59) SLC9A1
SCHEMBL8534963 0.85 SLC9A1 (0.78) SLC9A1
SCHEMBL8529024 0.84 SLC9A1 (0.76) SLC9A1
SCHEMBL8528508 0.84 SLC9A1 (0.76) SLC9A1
SCHEMBL8534275 0.83 SLC9A1 (0.74) SLC9A1
SCHEMBL8446483 0.82 SLC9A1 (0.54) SLC9A1
SCHEMBL8533960 0.82 SLC9A1 (0.73) SLC9A1
SCHEMBL8533480 0.82 SLC9A1 (0.73) SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699660-B1 Arylbenzoylguanidines MERCK PATENT GMBH (DE) 1998-10-28 EP disclosed
US-5807896-A Arylbenzoylguanidines MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) 1998-09-15 US disclosed
EP-0699660-A2 Arylbenzoylguanidines MERCK PATENT GmbH (DE) 1996-03-06 EP disclosed