Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533204 | 0.99 | SLC9A1 (0.48) | SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8530357 | 0.95 | SLC9A1 (0.51) | SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8532639 | 0.91 | SLC9A1 (0.48) | SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8529433 | 0.91 | SLC9A1 (0.48) | SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8534691 | 0.90 | SLC9A1 (0.47) | SLC9A1 | |
| SCHEMBL8533787 | 0.86 | SLC9A1 (0.49) | SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8533174 | 0.85 | SLC9A1 (0.47) | SLC9A1 | |
| SCHEMBL8534285 | 0.84 | SLC9A1 (0.42) | SLC9A1 | |
| SCHEMBL8530907 | 0.84 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL8532810 | 0.83 | SLC9A1 (0.43) | SLC9A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | claimed |
| EP-0699663-B1 | Alkyl-benzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1998-11-04 | — | — | EP | claimed |
| EP-0699663-A1 | Alkyl-benzoylguanidine derivatives | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | claimed |
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0699663-B1 | Alkyl-benzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1998-11-04 | — | — | EP | disclosed |
| EP-0699663-A1 | Alkyl-benzoylguanidine derivatives | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |