Sugi Predict

Sugi Predict / Compounds / SCHEMBL8533528

SCHEMBL8533528

SCHEMBL8533528

COc1ccc(C(OC[C@@]2(C=O)O[C@@]([SiH3])(n3cc(C)c(=O)[nH]c3=O)C[C@@H]2OC(C)(C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TK2 O00142 13/20 0.36
▸ TK1 P04183 8/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536619 0.89 TK2 (0.34) TK2TK1
SCHEMBL8532615 0.86 TK2 (0.35) TK2TK1
SCHEMBL8537328 0.84 TK2 (0.32) TK2TK1
SCHEMBL8536060 0.80 TK1 (0.33) TK1
SCHEMBL8533524 0.73 TK2 (0.36) TK2TK1
SCHEMBL9197110 0.73 TK2 (0.36) TK2TK1
SCHEMBL30631042 0.68 TK2 (0.42) TK2TK1
SCHEMBL6830774 0.67 TYMP (0.42) TK2TK1
SCHEMBL8348313 0.66 TK2 (0.42) TK2TK1
SCHEMBL8345447 0.66 TK2 (0.42) TK2TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750343-A Methods of detecting nucleic acids with nucleotide probes containing 4'-substituted nucleotides and kits therefor SYNTEX INC. (US) 1998-05-12 — — US disclosed