Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.63 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181561 | 1.00 | RARB (0.71) | RARBTP53TSHRKCNH2HRH3 | |
| SCHEMBL5351127 | 1.00 | RARB (0.71) | RARBTP53TSHRKCNH2HRH3 | |
| SCHEMBL13527301 | 0.98 | RARB (0.68) | RARBTP53TSHRKCNH2HRH3 | |
| SCHEMBL14672532 | 0.95 | TP53 (0.69) | RARBTP53TSHRPLA2G4BNPC1 | |
| SCHEMBL5215917 | 0.95 | TP53 (0.69) | RARBTP53TSHRPLA2G4BNPC1 | |
| SCHEMBL5215164 | 0.95 | TP53 (0.69) | RARBTP53TSHRPLA2G4BNPC1 | |
| SCHEMBL9636880 | 0.95 | TP53 (0.69) | RARBTP53TSHRPLA2G4BNPC1 | |
| SCHEMBL7342399 | 0.95 | KCNH2 (0.67) | RARBTP53TSHRKCNH2HRH3 | |
| SCHEMBL5219438 | 0.95 | TP53 (0.69) | RARBTP53TSHRPLA2G4BNPC1 | |
| SCHEMBL11126885 | 0.95 | TP53 (0.69) | RARBTP53TSHRPLA2G4BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1090155-A | — | — | None | — | — | JP | disclosed |
| US-5776365-A | COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST | MITSUI CHEMICALS, INC. (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5725798-A | CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| JP-S6490155-A | OPTICALLY ACTIVE ESTERS | ADEKA ARGUS CHEMICAL CO LTD | 1989-04-06 | — | — | JP | disclosed |