SCHEMBL8533732

SCHEMBL8533732

CCCCCC[C@@H](C)OC(=O)c1ccc(C(=O)OCc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
KMT2A Q03164 4/20 0.54
TDP1 Q9NUW8 2/20 0.54
SLC6A2 P23975 1/20 0.54
SLC6A3 Q01959 1/20 0.54
LMNA P02545 2/20 0.54
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
RAB9A P51151 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
GAA P10253 1/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
CETP P11597 3/20 0.48
SIRT2 Q8IXJ6 2/20 0.45
SIRT1 Q96EB6 2/20 0.45
NPC1 O15118 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799716 0.88 ALDH1A1 (0.57) ALDH1A1LMNAL3MBTL1TSHR
SCHEMBL3717165 0.88 KMT2A (0.51) ALDH1A1KMT2ATDP1SLC6A2SLC6A3
SCHEMBL3719289 0.88 KMT2A (0.51) ALDH1A1KMT2ATDP1SLC6A2SLC6A3
SCHEMBL9346509 0.88 ALDH1A1 (0.57) ALDH1A1LMNAL3MBTL1TSHR
SCHEMBL26189872 0.88 ALDH1A1 (0.74) ALDH1A1KMT2ATDP1LMNAHPGD
SCHEMBL2362569 0.87 ALDH1A1 (0.72) ALDH1A1KMT2ALMNAL3MBTL1TSHR
SCHEMBL12083567 0.87 ALDH1A1 (0.72) ALDH1A1KMT2ALMNAL3MBTL1TSHR
SCHEMBL1142463 0.87 ALDH1A1 (0.72) ALDH1A1KMT2ALMNAL3MBTL1TSHR
SCHEMBL1142467 0.87 ALDH1A1 (0.72) ALDH1A1KMT2ALMNAL3MBTL1TSHR
SCHEMBL27262020 0.87 ALDH1A1 (0.72) ALDH1A1KMT2ALMNAL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776365-A COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST MITSUI CHEMICALS, INC. (JP) 1998-07-07 US disclosed
US-5725798-A CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed
EP-0566379-B1 Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element MITSUI PETROCHEMICAL IND (JP) 1997-07-23 EP disclosed
US-5346646-A Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-13 US disclosed
EP-0566379-A2 Tetralin compound, liquid crystal material, liquid crystal composition and liquid crystal element MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-20 EP disclosed