Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.62 |
| ▸ | RELA | Q04206 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | RARB | P10826 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | ACR | P10323 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617383 | 1.00 | NPC1 (0.62) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10621463 | 0.96 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9711812 | 0.96 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10624408 | 0.96 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL8564258 | 0.96 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9711808 | 0.96 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL8642648 | 0.96 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10553827 | 0.96 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL11656366 | 0.96 | NPC1 (0.66) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL10611097 | 0.93 | NPC1 (0.59) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387059-B1 | Process of aligning liquid crystal media | HERCULES INC (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5589100-A | LIQUID CRYSTAL DISPLAY SUBSTRATES WITH ARYLAZO OR POLYARYLAZO DYES | HERCULES INCORPORATED (US) | 1996-12-31 | — | — | US | disclosed |
| US-5389285-A | Liquid crystal coupled dichroic dyes | HERCULES INCORPORATED (US) | 1995-02-14 | — | — | US | disclosed |
| US-5326865-A | Arylazo and poly(arylazo) dyes having at least one core radical selected from naphthyl or anthracyl and having at least one 2,3-dihydro-1,3-dialkyl perimidine substituent | HERCULES INCORPORATED (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0460504-B1 | Dichroic azo dyes | HERCULES INC (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5097029-A | Hydrolysis, alkylation, intermediates for azo dyes | HERCULES INCORPORATED (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0460504-A1 | Dichroic azo dyes | HERCULES INCORPORATED (US) | 1991-12-11 | — | — | EP | disclosed |
| US-5032009-A | Polarized light exposure | HERCULES INCORPORATED (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0432735-A2 | Liquid crystal coupled dichroic dyes | HERCULES INCORPORATED (US) | 1991-06-19 | — | — | EP | disclosed |
| EP-0406812-A2 | Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine | HERCULES INCORPORATED (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4974941-A | Process of aligning and realigning liquid crystal media | HERCULES INCORPORATED (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0387059-A2 | Process of aligning liquid crystal media | HERCULES INCORPORATED (US) | 1990-09-12 | — | — | EP | disclosed |