Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | USP5 | P45974 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686001 | 0.91 | SMN1; SMN2 (0.62) | SMN1; SMN2HPGDKDM4EKMT2AUSP5 | |
| SCHEMBL28594420 | 0.89 | TSHR (0.67) | SMN1; SMN2KMT2ATP53TSHRUSP5 | |
| SCHEMBL822901 | 0.84 | NR4A2 (0.68) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL3141694 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDKDM4EKMT2AUSP5 | |
| SCHEMBL822848 | 0.83 | KMT2A (0.70) | SMN1; SMN2HPGDKDM4EKMT2ATP53 | |
| SCHEMBL8532385 | 0.83 | HSD17B3 (0.67) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL4489664 | 0.82 | NR4A2 (0.71) | SMN1; SMN2HPGDKDM4EKMT2ATP53 | |
| SCHEMBL8206307 | 0.82 | NR4A2 (0.71) | SMN1; SMN2HPGDKMT2ATP53TSHR | |
| SCHEMBL8534650 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL2632728 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |