Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.57 |
| ▸ | CPT1A | P50416 | 1/20 | 0.57 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 11/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533037 | 1.00 | CPT2 (0.57) | CPT2CPT1ACPT1BPLA2G4ALTB4R | |
| SCHEMBL8532687 | 0.95 | CPT2 (0.53) | CPT2CPT1ACPT1B | |
| SCHEMBL8536461 | 0.94 | PLA2G4A (0.61) | CPT2CPT1ACPT1BPLA2G4ALTB4R | |
| SCHEMBL8532300 | 0.90 | CPT1A (0.52) | CPT2CPT1ACPT1B | |
| SCHEMBL3674759 | 0.88 | PLA2G4A (0.59) | CPT2CPT1ACPT1BPLA2G4A | |
| SCHEMBL8536303 | 0.87 | EPHX2 (0.48) | — | |
| SCHEMBL6723264 | 0.87 | PLA2G4A (0.71) | CPT2CPT1ACPT1BPLA2G4ALTB4R | |
| SCHEMBL29660323 | 0.87 | PLA2G4A (0.71) | CPT2CPT1ACPT1BPLA2G4ALTB4R | |
| SCHEMBL9372298 | 0.86 | CPT2 (0.46) | CPT2CPT1ACPT1B | |
| SCHEMBL9489472 | 0.86 | CPT1A (0.49) | CPT2CPT1ACPT1BPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432984-B1 | Carbamoyl derivatives | ZENECA LTD (GB) | 1998-03-04 | — | — | EP | disclosed |
| US-5334765-A | Intermediate for leukotriene antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |
| US-5286740-A | Leukotrine antagonists; antiinflammatory agnets, antiallergens, treating asthma | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | disclosed |
| EP-0432984-A2 | Carbamoyl derivatives | ZENECA LIMITED (GB) | 1991-06-19 | — | — | EP | disclosed |