Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 9/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 9/20 | 0.53 |
| ▸ | ITGAL | P20701 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531538 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2AITGB2 | |
| SCHEMBL8533324 | 0.88 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1KMT2AITGB2 | |
| SCHEMBL8530466 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2AITGB2 | |
| SCHEMBL11285580 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL3165346 | 0.80 | ITGB2 (0.72) | ALDH1A1MAPTMEN1KMT2AITGB2 | |
| SCHEMBL8533499 | 0.80 | HPGD (0.48) | ALDH1A1MAPTMEN1KMT2AICAM1 | |
| SCHEMBL6070125 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8532042 | 0.78 | HPGD (0.56) | ALDH1A1MAPTMEN1KMT2AITGB2 | |
| SCHEMBL4437995 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2AITGB2 | |
| SCHEMBL8610734 | 0.77 | HPGD (0.44) | ALDH1A1MAPTMEN1KMT2AITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |