Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675027 | 0.87 | MAPT (0.47) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL30002654 | 0.81 | MAPT (0.45) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL10472926 | 0.81 | MAPT (0.45) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL3449671 | 0.81 | MAPT (0.47) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL10129547 | 0.81 | GAA (0.48) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL405926 | 0.79 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL7746026 | 0.79 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL8466527 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL21684641 | 0.77 | MAPT (0.44) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL7247838 | 0.77 | GAA (0.41) | ALDH1A1GAAMAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839053-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF EGF RECEPTOR ASSOCIATED CANCERS AND PURIFICATION OF THE EGF RECEPTOR | GlycoTech Corp. (US) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003701-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF EGF RECEPTOR ASSOCIATED CANCERS AND PURIFICATION OF THE EGF RECEPTOR | GLYCOTECH CORP. (US) | 1997-02-06 | — | — | WO | disclosed |