Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.53 |
| ▸ | MTOR | P42345 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537286 | 0.87 | MAPT (0.58) | MAPTLMNATSHRHTTNPSR1 | |
| SCHEMBL3278610 | 0.86 | LMNA (0.57) | MAPTLMNATSHRHTTNPSR1 | |
| SCHEMBL8533688 | 0.86 | LMNA (0.57) | MAPTLMNATSHRHTTNPSR1 | |
| SCHEMBL8538662 | 0.83 | TSHR (0.65) | MAPTLMNATSHRHTTNPSR1 | |
| SCHEMBL8535901 | 0.82 | MAPT (0.53) | MAPTLMNATSHRHTTNPSR1 | |
| SCHEMBL8535151 | 0.81 | LMNA (0.56) | MAPTLMNATSHRHTTNPSR1 | |
| SCHEMBL8534074 | 0.79 | TSHR (0.86) | MAPTLMNATSHRHTTNPSR1 | |
| SCHEMBL8536340 | 0.79 | TSHR (0.86) | MAPTLMNATSHRHTTNPSR1 | |
| SCHEMBL8538515 | 0.79 | TSHR (0.56) | MAPTLMNATSHRHTTNPSR1 | |
| SCHEMBL8536287 | 0.79 | LMNA (0.50) | MAPTLMNATSHRHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629622-B1 | S-TRIAZINE DERIVATIVE AND REMEDY FOR ESTROGEN-DEPENDENT DISEASES CONTAINING THE SAME AS ACTIVE INGREDIENT | ZENYAKU KOGYO KK (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5489591-A | INHIBITORS OF AROMATASE; TREATING ENDOMETRIOSIS, BREAST CANCER CYSTIC OVARIES | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0629622-A1 | s-TRIAZINE DERIVATIVE AND REMEDY FOR ESTROGEN-DEPENDENT DISEASES CONTAINING THE SAME AS ACTIVE INGREDIENT | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1994-12-21 | — | — | EP | disclosed |