SCHEMBL8533980

SCHEMBL8533980

C=CCSCc1ccc(CSCC=C)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.40
ALOX5 P09917 1/20 0.40
PGR P06401 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
NR3C1 P04150 2/20 0.33
ALDH1A1 P00352 3/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
HTT P42858 3/20 0.32
LMNA P02545 2/20 0.32
GAA P10253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9280807 0.85 CYP1A2 (0.69) CYP1A2CYP2C9CYP2C19SMN1; SMN2L3MBTL1
Triphenylene SCHEMBL28111562 0.80 SMN1; SMN2 (0.58) CYP1A2CYP2C9CYP2C19SMN1; SMN2ALOX5
SCHEMBL11666602 0.79 CYP1A2 (0.43) CYP1A2CYP2C9CYP2C19
SCHEMBL30956073 0.77 MAOB (0.42) CYP1A2CYP2C9CYP2C19ALDH1A1CYP2D6
SCHEMBL8098004 0.76 MEN1 (0.38) CYP1A2CYP2C9CYP2C19SMN1; SMN2ALOX5
SCHEMBL45129 0.76 HSPA5 (0.45) SMN1; SMN2ALOX5ALDH1A1CYP2D6HPGD
SCHEMBL1121965 0.74 CYP2C19 (0.44) CYP1A2CYP2C9CYP2C19SMN1; SMN2ALOX5
SCHEMBL9496858 0.73 DPP4 (0.46) SMN1; SMN2ALOX5PGRL3MBTL1NR3C1
Phosphine SCHEMBL28217429 0.71 CYP2C19 (0.41) CYP1A2CYP2C9CYP2C19SMN1; SMN2ALOX5
SCHEMBL8793202 0.71 CYP1A2 (0.51) CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817430-A POLYARYLENEVINYLENE POLYMER XEROX CORPORATION (US) 1998-10-06 US claimed
US-5876865-A POLYARYLENEVINYLENE RESIN XEROX CORPORATION (US) 1999-03-02 US disclosed
US-5817430-A POLYARYLENEVINYLENE POLYMER XEROX CORPORATION (US) 1998-10-06 US disclosed