Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1351234 | 0.81 | CYP1A2 (0.48) | MEN1KMT2APOLBSMN1; SMN2CYP1A2 | |
| SCHEMBL7992841 | 0.78 | POLB (0.41) | MEN1KMT2APOLBSMN1; SMN2CYP1A2 | |
| SCHEMBL45129 | 0.77 | HSPA5 (0.45) | SMN1; SMN2ALOX5CYP2D6TSHRALDH1A1 | |
| SCHEMBL8533980 | 0.76 | CYP1A2 (0.45) | MEN1KMT2ASMN1; SMN2ALOX5CYP1A2 | |
| SCHEMBL9280807 | 0.74 | CYP1A2 (0.69) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL9496858 | 0.74 | DPP4 (0.46) | KMT2ASMN1; SMN2ALOX5ALDH1A1L3MBTL1 | |
| SCHEMBL11052 | 0.73 | GABRA1 (0.47) | MEN1KMT2APOLBSMN1; SMN2CYP3A4 | |
| SCHEMBL10954298 | 0.72 | CYP1A2 (0.63) | MEN1KMT2APOLBSMN1; SMN2CYP1A2 | |
| SCHEMBL28861078 | 0.72 | POLB (0.46) | MEN1KMT2APOLBSMN1; SMN2CYP3A4 | |
| Water SCHEMBL10657212 | 0.71 | GABRA1 (0.45) | MEN1KMT2APOLBSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057456-A | CATALYTIC REACTION USING BASE AND METAL CATALYST FOR REACTION | YALE UNIVERSITY (US) | 2000-05-02 | — | — | US | claimed |
| US-5977361-A | Transition metal-catalyzed process for preparing N-aryl compounds | YALE UNIVERSITY (US) | 1999-11-02 | — | — | US | claimed |
| EP-0143768-B1 | PREPARATION OF ORTHO-(ALKYLTHIOMETHYL) ANILINES BY CATALYTIC SULFILIMINE REARRANGEMENT | Monsanto Company (US) | 1987-05-06 | — | — | EP | claimed |
| US-4480130-A | Preparation of ortho-(alkylthiomethyl) anilines by catalytic sulfilimine rearrangement | MONSANTO COMPANY (US) | 1984-10-30 | — | — | US | claimed |
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5977361-A | Transition metal-catalyzed process for preparing N-aryl compounds | YALE UNIVERSITY (US) | 1999-11-02 | — | — | US | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0143768-A1 | Preparation of ortho-(alkylthiomethyl) anilines by catalytic sulfilimine rearrangement | Monsanto Company (US) | 1985-06-05 | — | — | EP | disclosed |