Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135913 | 1.00 | MAOB (0.38) | MAOBCHRNA7USP28USP25SLC6A2 | |
| SCHEMBL7137289 | 1.00 | MAOB (0.38) | MAOBCHRNA7USP28USP25SLC6A2 | |
| SCHEMBL7140321 | 0.84 | SLC6A2 (0.45) | MAOBCHRNA7USP28USP25SLC6A2 | |
| SCHEMBL7136382 | 0.84 | SLC6A2 (0.45) | MAOBCHRNA7USP28USP25SLC6A2 | |
| SCHEMBL7133285 | 0.81 | MAOB (0.39) | MAOBCHRNA7SLC6A2SLC6A4L3MBTL1 | |
| SCHEMBL7139327 | 0.81 | MAOB (0.39) | MAOBCHRNA7SLC6A2SLC6A4L3MBTL1 | |
| SCHEMBL7133283 | 0.81 | MAOB (0.39) | MAOBCHRNA7SLC6A2SLC6A4L3MBTL1 | |
| SCHEMBL8791980 | 0.78 | SLC18A3 (0.39) | MAOBCHRNA7HTTCARM1HRH3 | |
| SCHEMBL4715366 | 0.77 | SLC6A2 (0.44) | CHRNA7SLC6A2SLC6A4L3MBTL1CARM1 | |
| SCHEMBL7132227 | 0.75 | SLC6A2 (0.39) | MAOBUSP28USP25SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807866-A | Process for preparing N-benzyl indoles | THE UNIVERSITY OF EAST ANGLIA (GB) | 1998-09-15 | — | — | US | disclosed |
| EP-0775694-A2 | Process for preparing N-benzyl indoles | University of East Anglia (GB) | 1997-05-28 | — | — | EP | disclosed |