SCHEMBL8534128

SCHEMBL8534128

OCC(O)COC1CCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.43
PRMT5 O14744 2/20 0.42
WDR77 Q9BQA1 2/20 0.42
HTT P42858 4/20 0.40
MAPT P10636 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 6/20 0.38
LMNA P02545 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RGS12 O14924 1/20 0.37
APOBEC3A P31941 2/20 0.35
APOBEC3G Q9HC16 2/20 0.35
USP2 O75604 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9132499 0.98 KDM4E (0.45) KDM4EPRMT5WDR77HTTMAPT
SCHEMBL3815044 0.98 KDM4E (0.45) KDM4EPRMT5WDR77HTTMAPT
Water SCHEMBL29022494 0.96 KDM4E (0.44) KDM4EPRMT5WDR77HTTMAPT
SCHEMBL22631553 0.95 HTT (0.40) KDM4EPRMT5WDR77HTTMAPT
SCHEMBL6230438 0.91 MEN1 (0.42) KDM4EPRMT5WDR77HTTMAPT
SCHEMBL27303664 0.91
SCHEMBL13907638 0.86 KDM4E (0.49) KDM4EPRMT5WDR77HTTMAPT
SCHEMBL20794136 0.86 USP2 (0.50) KDM4EPRMT5WDR77HTTMAPT
SCHEMBL4262966 0.85 KDM4E (0.37) KDM4EPRMT5WDR77HTTMAPT
SCHEMBL23530308 0.83 MEN1 (0.38) KDM4EPRMT5WDR77HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795239-B Topical composition 帝斯曼知识产权资产管理有限公司 2023-10-13 CN disclosed
EP-3965722-B1 TOPICAL COMPOSITIONS WITH PRESERVATIVE SYSTEM DSM IP ASSETS BV (NL) 2023-08-16 EP disclosed
EP-3965721-B1 TOPICAL COMPOSITIONS WITH ANTIMICROBIAL AGENT MIXTURE DSM IP ASSETS BV (NL) 2023-06-14 EP disclosed
US-20220296480-A1 TOPICAL COMPOSITIONS DSM IP ASSETS B.V. (NL) 2022-09-22 US disclosed
US-20220211594-A1 TOPICAL COMPOSITIONS DSM IP ASSETS B.V. (NL) 2022-07-07 US disclosed
EP-3965721-A1 TOPICAL COMPOSITIONS DSM IP Assets B.V. (NL) 2022-03-16 EP disclosed
EP-3965722-A1 TOPICAL COMPOSITIONS DSM IP Assets B.V. (NL) 2022-03-16 EP disclosed
CN-113795238-A Topical compositions 帝斯曼知识产权资产管理有限公司 2021-12-14 CN disclosed
CN-113795239-A External composition 帝斯曼知识产权资产管理有限公司 2021-12-14 CN disclosed
WO-2020229259-A1 TOPICAL COMPOSITIONS DSM IP ASSETS B.V. (NL) 2020-11-19 WO disclosed
WO-2020229262-A1 TOPICAL COMPOSITIONS DSM IP ASSETS B.V. (NL) 2020-11-19 WO disclosed
EP-3735958-A1 TOPICAL COMPOSITIONS WITH PRESERVATION SYSTEM DSM IP Assets B.V. (NL) 2020-11-11 EP disclosed
CN-1436890-A Concentrated & stable fabric softening composition containing chelant PROCTER & GAMBLE (US) 2003-08-20 CN disclosed
CN-1107716-C Concentrated stable fabric softening compositions comprising chelants PROCTER & GAMBLE (US) 2003-05-07 CN disclosed
CN-1098350-C Fabric softening compound/composition PROCTER & GAMBLE (US) 2003-01-08 CN disclosed
CN-1219953-A Fabric softening compound/composition PROCTER & GAMBLE (US) 1999-06-16 CN disclosed
CN-1196082-A Concentrated stable fabric softening compositions comprising chelants PROCTER & GAMBLE (US) 1998-10-14 CN disclosed
EP-0839179-A1 CONCENTRATED, WATER DISPERSIBLE, STABLE, FABRIC SOFTENING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-05-06 EP disclosed
US-5747443-A BIODEGRADABLE QUATERNARY AMMONIUM COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1998-05-05 US disclosed
WO-1997003170-A1 CONCENTRATED, WATER DISPERSIBLE, STABLE, FABRIC SOFTENING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-01-30 WO disclosed