Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536033 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTGPR52NPC1POLB | |
| SCHEMBL8534126 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTGPR52NPC1POLB | |
| SCHEMBL3887709 | 0.88 | RECQL (0.59) | SMN1; SMN2MAPTNPC1POLBRAB9A | |
| SCHEMBL6947075 | 0.84 | MAPT (0.64) | SMN1; SMN2MAPTGPR52NPC1POLB | |
| SCHEMBL14124718 | 0.84 | MAPT (0.64) | SMN1; SMN2MAPTGPR52NPC1POLB | |
| SCHEMBL6947073 | 0.84 | MAPT (0.64) | SMN1; SMN2MAPTGPR52NPC1POLB | |
| SCHEMBL14124738 | 0.84 | MAPT (0.64) | SMN1; SMN2MAPTGPR52NPC1POLB | |
| SCHEMBL28342923 | 0.81 | GPR52 (0.54) | SMN1; SMN2MAPTGPR52NPC1POLB | |
| SCHEMBL10940642 | 0.80 | GPR52 (0.50) | SMN1; SMN2MAPTGPR52NPC1POLB | |
| SCHEMBL10940645 | 0.80 | GPR52 (0.50) | SMN1; SMN2MAPTGPR52NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |