Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531622 | 0.89 | MAPT (0.52) | MAPTSMN1; SMN2L3MBTL1HPGDPTPN1 | |
| SCHEMBL8533747 | 0.88 | MAPT (0.58) | MAPTSMN1; SMN2L3MBTL1HPGDPTPN1 | |
| SCHEMBL6966057 | 0.85 | MAPT (0.63) | MAPTSMN1; SMN2L3MBTL1HPGDPTPN1 | |
| SCHEMBL20142949 | 0.80 | GSK3B (0.52) | SMN1; SMN2L3MBTL1HPGDGSK3BALDH1A1 | |
| SCHEMBL31063861 | 0.80 | KMT2A (0.47) | MAPTSMN1; SMN2L3MBTL1HPGDPTPN1 | |
| SCHEMBL27839718 | 0.78 | SMN1; SMN2 (0.58) | MAPTSMN1; SMN2L3MBTL1HPGDPTPN1 | |
| SCHEMBL7633456 | 0.77 | MAPT (0.53) | MAPTSMN1; SMN2L3MBTL1HPGDPTPN1 | |
| SCHEMBL6515543 | 0.76 | MAPT (0.42) | MAPTSMN1; SMN2L3MBTL1HPGDPTPN1 | |
| SCHEMBL28651153 | 0.76 | KMT2A (0.50) | MAPTSMN1; SMN2L3MBTL1HPGDPTPN1 | |
| SCHEMBL16284851 | 0.75 | SMN1; SMN2 (0.66) | MAPTSMN1; SMN2L3MBTL1HPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |