Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 3/20 | 0.84 |
| ▸ | RAB9A | P51151 | 2/20 | 0.84 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.67 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.62 |
| ▸ | FEN1 | P39748 | 1/20 | 0.62 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenbufen SCHEMBL11329267 | 0.91 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 | |
| Fenbufen SCHEMBL25117 | 0.91 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 | |
| Fenbufen SCHEMBL11393779 | 0.90 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 | |
| SCHEMBL719034 | 0.88 | NR4A2 (0.85) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 | |
| SCHEMBL30121738 | 0.88 | NR4A2 (0.85) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 | |
| SCHEMBL8534650 | 0.88 | SMN1; SMN2 (0.72) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 | |
| SCHEMBL11798285 | 0.88 | SMN1; SMN2 (0.72) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 | |
| SCHEMBL11798279 | 0.88 | SMN1; SMN2 (0.72) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 | |
| SCHEMBL2632728 | 0.88 | SMN1; SMN2 (0.72) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 | |
| SCHEMBL11507228 | 0.87 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNARAB9AFFAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |