Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.66 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.66 |
| ▸ | ITGAL | P20701 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534354 | 0.91 | ATM (0.69) | SLC6A4SLC6A2SLC6A3KDM4EATM | |
| SCHEMBL8535269 | 0.88 | SLC6A4 (0.70) | SLC6A4SLC6A2SLC6A3KDM4EATM | |
| SCHEMBL5732433 | 0.85 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3LMNATDP1 | |
| Hydrochloric Acid SCHEMBL9464818 | 0.84 | SLC6A4 (0.97) | SLC6A4SLC6A2SLC6A3KDM4EATM | |
| SCHEMBL9541406 | 0.84 | SLC6A4 (0.92) | SLC6A4SLC6A2SLC6A3ITGB2ICAM1 | |
| Hydrochloric Acid SCHEMBL9541705 | 0.82 | SLC6A4 (0.89) | SLC6A4SLC6A2SLC6A3KDM4EATM | |
| SCHEMBL8533948 | 0.82 | SLC6A4 (0.79) | SLC6A4SLC6A2SLC6A3LMNATDP1 | |
| SCHEMBL9541450 | 0.81 | SLC6A4 (0.82) | SLC6A4SLC6A2SLC6A3KDM4EATM | |
| SCHEMBL9541726 | 0.81 | SLC6A4 (0.76) | SLC6A4SLC6A2SLC6A3LMNATDP1 | |
| SCHEMBL9541658 | 0.81 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |