Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.82 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9541441 | 0.99 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3ATMPLA2G1B | |
| SCHEMBL9541406 | 0.92 | SLC6A4 (0.92) | SLC6A4SLC6A2SLC6A3LMNAALDH1A1 | |
| SCHEMBL5732433 | 0.90 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9541705 | 0.90 | SLC6A4 (0.89) | SLC6A4SLC6A2SLC6A3ATMLMNA | |
| Hydrochloric Acid SCHEMBL9464818 | 0.89 | SLC6A4 (0.97) | SLC6A4SLC6A2SLC6A3ATMLMNA | |
| SCHEMBL4439230 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3ATMPLA2G1B | |
| SCHEMBL11632956 | 0.87 | SLC6A4 (0.74) | SLC6A4SLC6A2SLC6A3LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11634491 | 0.85 | SLC6A4 (0.72) | SLC6A4SLC6A2SLC6A3LMNAALDH1A1 | |
| SCHEMBL8535269 | 0.84 | SLC6A4 (0.70) | SLC6A4SLC6A2SLC6A3ATMPLA2G1B | |
| SCHEMBL8534673 | 0.81 | SLC6A4 (0.74) | SLC6A4SLC6A2SLC6A3ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012080-A1 | SUBSTITUTED DIPHENYLSULFIDES AS SEROTONIN UPTAKE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-24 | — | — | WO | claimed |
| WO-1993012080-A1 | SUBSTITUTED DIPHENYLSULFIDES AS SEROTONIN UPTAKE INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-24 | — | — | WO | disclosed |