Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921872 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAMAPK1HTTHSD11B1 | |
| SCHEMBL953585 | 0.85 | EPHX2 (0.46) | SMN1; SMN2GAAMAPK1HTTHSD11B1 | |
| SCHEMBL4719490 | 0.84 | GAA (0.59) | SMN1; SMN2GAAMAPK1HTTEPHX1 | |
| SCHEMBL13387564 | 0.84 | GAA (0.59) | SMN1; SMN2GAAMAPK1HTTEPHX1 | |
| SCHEMBL6015350 | 0.82 | EPHX1 (0.46) | SMN1; SMN2GAAMAPK1HTTHSD11B1 | |
| SCHEMBL1827279 | 0.81 | EPHX1 (0.64) | SMN1; SMN2GAAMAPK1HTTEPHX1 | |
| SCHEMBL26677284 | 0.81 | EPHX1 (0.59) | SMN1; SMN2GAAMAPK1HTTEPHX1 | |
| SCHEMBL16377759 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2GAAMAPK1HTTHSD11B1 | |
| SCHEMBL30364252 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAMAPK1HTTHSD11B1 | |
| SCHEMBL2801497 | 0.80 | EPHX1 (0.67) | SMN1; SMN2GAAMAPK1HTTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537201-B1 | 1-[4-(IMIDAZOL-1-YL)BENZOYL]PIPERIDINE DERIVATIVES AS ANTIARRHYTHMIC AGENTS | SCHERING AG (DE) | 1998-11-18 | — | — | EP | disclosed |
| EP-0537201-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5189036-A | Cardiovascular agents; class III antiarrhythmic agents | SCHERING AG (DE) | 1993-02-23 | — | — | US | disclosed |
| WO-1991019709-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-12-26 | — | — | WO | disclosed |