Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.66 |
| ▸ | CCKAR | P32238 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534795 | 1.00 | CCKBR (0.66) | CCKBRCCKARKMT2AALDH1A1MAPT | |
| SCHEMBL9867205 | 1.00 | CCKBR (0.66) | CCKBRCCKARKMT2AALDH1A1MAPT | |
| SCHEMBL9865895 | 0.87 | CCKBR (0.70) | CCKBRCCKAR | |
| SCHEMBL8536760 | 0.87 | CCKBR (0.70) | CCKBRCCKAR | |
| SCHEMBL8536757 | 0.87 | CCKBR (0.70) | CCKBRCCKAR | |
| SCHEMBL9573583 | 0.82 | CCKBR (0.47) | CCKBRCCKARALDH1A1 | |
| SCHEMBL8746489 | 0.81 | CCKBR (0.45) | CCKBRCCKAR | |
| SCHEMBL8746503 | 0.81 | CCKBR (0.45) | CCKBRCCKAR | |
| SCHEMBL8536547 | 0.81 | CCKBR (0.46) | CCKBRCCKAR | |
| SCHEMBL8536542 | 0.81 | CCKBR (0.46) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4820834-A | Benzodiazepine analogs | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |