Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301629 | 0.80 | CNR1 (0.59) | CNR2CNR1 | |
| SCHEMBL10650580 | 0.73 | MAPT (0.57) | POLBSMN1; SMN2CNR2CNR1MAPT | |
| SCHEMBL6449877 | 0.73 | HCRTR2 (0.53) | MAPTALDH1A1 | |
| SCHEMBL7504824 | 0.73 | HCRTR2 (0.53) | MAPTALDH1A1 | |
| SCHEMBL3677750 | 0.73 | HCRTR2 (0.53) | MAPTALDH1A1 | |
| SCHEMBL9303271 | 0.72 | MAPT (0.52) | CNR2CNR1MAPT | |
| SCHEMBL9302976 | 0.72 | CNR1 (0.54) | CNR2CNR1MAPT | |
| SCHEMBL27034080 | 0.71 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL15478844 | 0.71 | CNR2 (0.59) | CNR2CNR1MAPT | |
| SCHEMBL15478842 | 0.71 | CNR2 (0.75) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817651-A | ANALGESICS, RHEUMATIC DISEASES, ANTIINFLAMMATORY AGENTS | SANOFI (FR) | 1998-10-06 | — | — | US | disclosed |
| US-5068234-A | Analgesics, rheumatic diseases, antiinflammatory agents or antiglaucoma | STERLING DRUG INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0444451-A2 | 3-Arylcarbonyl-1H-indoles useful as therapeutic agents | STERLING WINTHROP INC. (US) | 1991-09-04 | — | — | EP | disclosed |