Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | ADH5 | P11766 | 2/20 | 0.50 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537664 | 0.85 | PDCD1 (0.52) | HTR2AHTR2CHTR2BLSSPDCD1 | |
| SCHEMBL8537672 | 0.84 | AHR (0.55) | HTR2AHTR2CHTR2BLSSPDCD1 | |
| SCHEMBL8536314 | 0.83 | LSS (0.50) | HTR2AHTR2CHTR2BLSSPDCD1 | |
| SCHEMBL8537654 | 0.83 | HTR2A (0.59) | HTR2AHTR2CHTR2BLSSADH5 | |
| SCHEMBL8534724 | 0.82 | LSS (0.48) | HTR2AHTR2CHTR2BLSSPDCD1 | |
| Hydrochloric Acid SCHEMBL8539581 | 0.81 | HTR2A (0.58) | HTR2AHTR2CHTR2BLSSADH5 | |
| SCHEMBL8534504 | 0.81 | LSS (0.52) | HTR2AHTR2CHTR2BLSSPDCD1 | |
| SCHEMBL8538842 | 0.81 | LSS (0.48) | HTR2AHTR2CHTR2BLSSPDCD1 | |
| SCHEMBL8537652 | 0.81 | CYP1A2 (0.47) | HTR2AHTR2CHTR2BLSSPDCD1 | |
| SCHEMBL8536934 | 0.81 | HTR2A (0.60) | HTR2AHTR2CHTR2BLSSADH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537201-B1 | 1-[4-(IMIDAZOL-1-YL)BENZOYL]PIPERIDINE DERIVATIVES AS ANTIARRHYTHMIC AGENTS | SCHERING AG (DE) | 1998-11-18 | — | — | EP | claimed |
| US-5189036-A | Cardiovascular agents; class III antiarrhythmic agents | SCHERING AG (DE) | 1993-02-23 | — | — | US | claimed |
| EP-0537201-B1 | 1-[4-(IMIDAZOL-1-YL)BENZOYL]PIPERIDINE DERIVATIVES AS ANTIARRHYTHMIC AGENTS | SCHERING AG (DE) | 1998-11-18 | — | — | EP | disclosed |
| US-5189036-A | Cardiovascular agents; class III antiarrhythmic agents | SCHERING AG (DE) | 1993-02-23 | — | — | US | disclosed |