Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238501 | 0.90 | HTT (0.71) | HTTMGLLHSD11B1MEN1KMT2A | |
| SCHEMBL7266828 | 0.81 | HTT (0.71) | HTTMGLLHSD11B1MEN1KMT2A | |
| SCHEMBL8532319 | 0.78 | HTT (0.68) | HTTKDM4ELMNAMAPTKDM2B | |
| SCHEMBL31279997 | 0.76 | NPC1 (0.62) | MGLLHSD11B1MEN1KMT2AMAPT | |
| Bicarbonate SCHEMBL11475794 | 0.74 | NPC1 (0.61) | MGLLHSD11B1MEN1KMT2AMAPT | |
| SCHEMBL3226999 | 0.74 | HTT (0.61) | HTTHSD11B1MEN1KMT2AHPGD | |
| SCHEMBL10801970 | 0.73 | MGLL (0.50) | MGLLHSD11B1MEN1KMT2ATP53 | |
| SCHEMBL8532097 | 0.72 | SMN1; SMN2 (0.44) | MGLLHSD11B1SIRT2MEN1KMT2A | |
| Acetic Acid SCHEMBL7604746 | 0.71 | NPC1 (0.62) | MGLLHSD11B1MEN1KMT2AMAPT | |
| SCHEMBL29002065 | 0.71 | SRD5A2 (0.64) | MGLLHSD11B1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |