Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 11/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | TK2 | O00142 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533223 | 1.00 | TYMP (0.51) | TYMPHSP90AA1P2RY6P2RY14NT5E | |
| SCHEMBL9220904 | 0.94 | HSP90AA1 (0.51) | TYMPHSP90AA1P2RY6P2RY14NT5E | |
| SCHEMBL9220896 | 0.94 | HSP90AA1 (0.51) | TYMPHSP90AA1P2RY6P2RY14NT5E | |
| SCHEMBL13205006 | 0.92 | TYMP (0.52) | TYMPTK2 | |
| SCHEMBL13714390 | 0.92 | TYMP (0.52) | TYMPTK2 | |
| SCHEMBL3068344 | 0.92 | TYMP (0.52) | TYMPTK2 | |
| SCHEMBL9219803 | 0.88 | HSP90AA1 (0.51) | TYMPHSP90AA1P2RY6P2RY14NT5E | |
| SCHEMBL9219798 | 0.88 | HSP90AA1 (0.51) | TYMPHSP90AA1P2RY6P2RY14NT5E | |
| SCHEMBL8534788 | 0.88 | TYMP (0.62) | TYMPHSP90AA1P2RY6P2RY14NT5E | |
| SCHEMBL8534790 | 0.88 | TYMP (0.62) | TYMPHSP90AA1P2RY6P2RY14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741900-A | REACTING PROTECTED FLUOROURIDINE WITH SUCCINIC ANHYDRIDE, ATTACHING TO LONG-CHAIN ALKYLAMINE CONTROLLED PORE GLASS IN ANHYDROUS PYRIDINE IN PRESENCE OF DIMETHYLAMINOPYRIDINE AND DIMETHYLAMINOPROPYL/ETHYLCARBODIIMIDE | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1998-04-21 | — | — | US | disclosed |