Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.43 |
| ▸ | WNT3A | P56704 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536465 | 0.82 | ERCC5 (0.42) | ERCC5FEN1CTNNB1WNT3AKMT2A | |
| SCHEMBL28037656 | 0.81 | HPGD (0.43) | HPGDKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL7799519 | 0.79 | KDM4E (0.58) | ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL7791486 | 0.79 | KDM4E (0.58) | ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL7799518 | 0.79 | KDM4E (0.58) | ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL10645702 | 0.78 | TSHR (0.62) | HPGDKMT2ASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL13647199 | 0.78 | ERCC5 (0.55) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| Hydrochloric Acid SCHEMBL27449428 | 0.78 | KDM4E (0.56) | ERCC5FEN1CTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL27449427 | 0.78 | KDM4E (0.56) | ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL4313955 | 0.78 | ERCC5 (0.51) | ERCC5FEN1CTNNB1WNT3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |