Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16042409 | 0.82 | HTT (0.48) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL8535216 | 0.81 | ERCC5 (0.53) | HPGDSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL5951330 | 0.79 | F2R (0.52) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL4227817 | 0.78 | NPC1 (0.50) | HPGDALDH1A1SMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL10645702 | 0.77 | TSHR (0.62) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL27419431 | 0.77 | KDM4E (0.56) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL27419430 | 0.77 | KDM4E (0.56) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL16148425 | 0.75 | CTNNB1 (0.51) | HPGDALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL28037644 | 0.75 | CTSD (0.49) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL29573770 | 0.72 | KMT2A (0.53) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164113-A | Pyrroloamide inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |